59 Articles found
American Society for Microbiology (ASM) Articles
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Ercc1-xpf endonuclease facilitates dna double-strand break repair
ERCC1-XPF endonuclease is required for nucleotide excision repair (NER) of helix-distorting DNA lesions. However, mutations in ERCC1 or XPF in humans or mice cause a more severe phenotype than absence of NER, prompting a search for novel repair ...
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Identification of the putative protein phosphatase gene PTC1 as a virulence-related gene using a silkworm model of candida albicans infection
Protein phosphatases are critical for the regulation of many cellular processes. Null mutants of 21 putative protein phosphatases of Candida albicans were constructed by consecutive allele replacement using the URA3 and ARG4 marker genes. A ...
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Sorting signals within the saccharomyces cerevisiae sporulation-specific dityrosine transporter, Dtr1p, c terminus promote golgi-to-prospore membrane transport
During sporulation in Saccharomyces cerevisiae, the dityrosine transporter Dtr1p, which is required for formation of the outermost layer of the spore wall, is specifically expressed and transported to the prospore membrane, a novel ...
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A protein with similarity to pten regulates aggregation territory size by decreasing cyclic amp pulse size during dictyostelium discoideum development
An interesting but largely unanswered biological question is how eukaryotic organisms regulate the size of multicellular tissues. During development, a lawn of Dictyostelium cells breaks up into territories, and within the territories the cells ...
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Dispersed mutations in histone H3 that affect transcriptional repression and chromatin structure of the CHA1 promoter in saccharomyces cerevisiae
The histone H3 amino terminus, but not that of H4, is required to prevent the constitutively bound activator Cha4 from remodeling chromatin and activating transcription at the CHA1 gene in Saccharomyces cerevisiae. Here we show that neither the ...
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Calcineurin target crza regulates conidial germination, hyphal growth, and pathogenesis of aspergillus fumigatus
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, Public Health Research Institute, International Center for ...
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Mitogen-activated protein kinase pathways and fungal pathogenesis
In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular signals and the regulation of different developmental processes. ...
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Mitogen-activated protein kinase pathways and fungal pathogenesis
In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular signals and the regulation of different developmental processes. ...
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Hyphal growth: a tale of motors, lipids, and the spitzenkorper
Filamentous fungi are a large and evolutionarily successful group of organisms of enormous ecological importance (27, 114). Fungi also have a considerable impact on our economy because they serve as bio-factories for the industrial production of ...
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Autophagy is activated for cell survival after endoplasmic reticulum stress
Eukaryotic cells deal with accumulation of unfolded proteins in the endoplasmic reticulum (ER) by the unfolded protein response, involving the induction of molecular chaperones, translational attenuation, and ER-associated degradation, to prevent ...
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Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice
Telomere length and function are crucial factors that determine the capacity for cell proliferation and survival, mediate cellular senescence, and play a role in malignant transformation in eukaryotic systems. The telomere length of a specific ...
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Use of plant growth-promoting bacteria for biocontrol of plant diseases: Principles, mechanisms of action, and future prospects
Pathogenic microorganisms affecting plant health are a major and chronic threat to food production and ecosystem stability worldwide. As agricultural production intensified over the past few decades, producers became more and more dependent on ...
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Use of plant growth-promoting bacteria for biocontrol of plant diseases: principles, mechanisms of action, and future prospects
Laboratoire de Stress, Défenses et Reproduction des Plantes, Unité de Recherche Vignes et Vins de Champagne, UPRES EA 2069, UFR Sciences, Université de Reims Champagne-Ardenne, 51687 Reims Cedex 2, France, Agroscope FAW Wädenswil, Swiss Federal ...
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The Kip3-Like Kinesin KipB moves along microtubules and determines spindle position during synchronized mitoses in aspergillus nidulans hyphae
Kinesins are motor proteins which are classified into 11 different families. We identified 11 kinesin-like proteins in the genome of the filamentous fungus Aspergillus nidulans. Relatedness analyses based on the motor domains grouped them into nine ...
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Molecular genetics of pathogenic oomycetes
Parasitic and pathogenic lifestyles have evolved repeatedly in eukaryotes (93). Several parasitic eukaryotes represent deep phylogenetic lineages, suggesting that they feature unique molecular processes for infecting their hosts. One such group is ...
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Controls morphogenesis, pheromone response, and pathogenicity in the fungal pathogen ustilago maydis
Ustilago maydis, a pathogen of maize, is a useful model for the analysis of mating, pathogenicity, and the morphological transition between budding and filamentous growth in fungi. As in other fungi, these processes are regulated by conserved ...
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Origin and production of acetoin during wine yeast fermentation
The flavor of alcoholic beverages is produced by a very large number of compounds (50). Among these, acetoin is important because of its involvement in the bouquet of wine, and it is the key compound in the biosynthesis of 2,3-butanediol and ...
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Isolation of a cold-sensitive fermentation mutant of a baker`s yeast strain and its use in a refrigerated dough process
Conventional baker`s yeast converts sugars in dough into CO2 and ethanol to a significant extent when the dough is stored for days at 5 degrees C. We have isolated Csf (cold-sensitive fermentation) mutants of a commercial baker`s yeast by a ...
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Interaction between the Cig1 and Cig2 B-type cyclins in the fission yeast cell cycle
In this report, we describe the cloning and characterization of a B-type cyclin, Cig2 from the fission yeast Schizosaccharomyces pombe. The cig2 gene encodes a 45-kDa protein that is most similar to a previously identified B-type cyclin in S. pombe, ...