BIOVET

- Chemical

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Diclazuril is a chemical anticoccidial,  a benzeneacetonitrile derivative – synthetic compound of  the triazinone family. Diclazuril  is  has  a  mode  of  action  completely  different  from  the  existing  ionophores  and  chemicals, available on the market. According to the anticoccidial properties of triazinones, diclazuril is active against intracellular  development stages of coccidia, namely during schizogony and gametogony. 

After diclurazil treatment, the first- and second-generation schizonts show extensive degenerative  changes  which  are  characterised  by  the  loss  of  internal  structure,  the  appearance  of  many  intracytoplasmic  vacuoles  and  incomplete  merogony.  Ultrastructural  findings  indicate  that  diclazuril  treatment  primarily  affects  the  normal  differentiation  of  the  respective  endogenous  stages  during  parasite  development.  This  leads  to  complete  degeneration  of  schizonts  and gamonts.

INDICATIONS
As an aid in the prevention of coccidiosis caused by Eimerio acervulino, E. bfunetti, E. maxima, E. mitis, E. praecox, E. necatrix and E. tenella in broiler chickens and chickens reared for laying. As an aid in the prevention of coccidiosis caused by Eimeria adenoeides, E. meleogfimitis and E. gallopavonis in turkeys for fattening.
As an aid in the prevention of coccidiosis caused by Eimeria iffesidua, Eimerio medio, Eimerio flovescens, Eimerio intestinolis, Eimerio perforons, Eimerio piriformis, Eimerio stiedoi, Eimerio mogno, E.exiguo ondE.coecicolo in rabbits for fattening and breeding. For the prevention of £ numidoe and £ grenieri in guinea fowls.

CONTRAINDICATIONS
No contraindications are known under correct usage of the product.

MODE OF ADMINISTRATION
Orally, mixing into the feed.Mix 200 gram of Clinacox® 0.5% premix per ton of complete feed. This results in a final concentration of 1 g diclazuril per ton of feed (1 ppm). To ensure thorough dispersion of the product, it should be mixed with a suitable quantity (20-25 kg) of feed ingredients before incorporation in the final mix.

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