- Livestock Vaccine - Bivalent E.Coli Vaccine



COLIDOLL is an oil adjuvanted inactive vaccine used in pregnant cattle in order to protect newborn calves against E.coli infections. Indications: The disease is caused by enterotoxigenic E.coli serotypes and it can be extremely fatal in newborn calves. The disaese cause to significant economical losess and it is seen worldwide. In pathogenesis of the disease, fimbrial antigens and enterotoxins of E.coli play an important role.  K99 and F41 antigens are commonly found in this type enterotoxigenic E.coli. COLIDOLL comprises all these antigenic components (EC (O101:H-K99+F41+) ve 11A (O?:H-K99+:,F(Y)+)  that play in the pathogenesis of the disease.

Composition per dose:

  • E.coli EC (O1O1: H-K99+F41+) strain: 1x1010CFU
  • E.coli 11A ( O?:H-K99+:, F(Y)+) strain: 1x1010CFU
  • Oil adjuvant: 1 ml
  • Formaldehyde (37%): 2 μl

Target Species: Pregnant cattles

Administration and dosage: COLIDOLL is administered to pregnant cattle 2 ml by subcutaneous route twice. There should be 3-4 weeks interval between two vaccinations and last vaccination should be administered minumum 3 weeks before calving.

Packing: Vials of 5, 10, 25 and 50 doses with its corresponding diluents in glass bottles.

Storage: Store in a cool place (2 ºC – 8 ºC). Do not freeze. Protect from light.

Destruction conditions: All used bottles should be disposed of in accordance with local requirements of Medicinal Wastes Control Legislation.

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