PSL - Model GFD® Lab Nutsche - Laboratory Filter Dryer
From Filter Dryer Systems
The GFD®Lab is a benchtop Agitated Nutsche Filter Dryer (ANFD) that efficiently performs laboratory solid-liquid separation processes. It is a miniature version of a production filter-dryer, allowing effective filtration and drying with the same reliability and benefits as full-size PSL ANFD filter dryers.
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It is designed to overcome well-known production c...
It is designed to overcome well-known production challenges faced by manufacturers when using traditional production methods such as Büchner filtration and oven tray-drying and is the ideal technology to successfully complete scale-up and scale-down activities and to obtain predictive performance results.
The GFD®Lab consists of an agitated vessel designed to work under vacuum and under pressure. The vessel can be made of either glass, stainless steel or Alloy-22 and has a heated jacket for efficient drying. Solid-liquid separation is performed within its unique filtration basket, which can be removed to ease and maximise product collection.
The GFD®Lab is serving research institutes, laboratories, universities and companies from a wide range of industries. The technology is assisting scientists and process engineers to innovate and optimise their unique processes, worldwide.
A filter dryer combines two processing steps within a single piece of equipment. Firstly, solid-liquid separation is carried out, also known as filtration. The second step often consists of washing the product for removing impurities and/or solvent traces. The final step is to dry the collected solids.
In the majority of cases the solid is the product of interest but filter dryer technology can also be used in processes where the filtrate (liquid) is the valuable product. It is also possible to retain both the solid and the filtrate, if required.
- A fully sealed vessel which can be pressurised or put under vacuum.
- A bi-directional agitator within the vessel with a height-adjustable blade to account for variable product cake thicknesses.
- A filtering element at the base of the vessel, usually mesh.
- Temperature controlled zones including heated jackets and in some cases a heated agitator.
The Agitator within Nutsche Filter Dryers provides superior performance over traditional methods such as Buchner Filtration and Tray Dryers by offering the following features.
- Preventing heavy build-up on the filtration screen by keeping the product in motion in order to keep a rapid filtration rate.
- Maintaining efficient pressure filtration by smoothing the top surface of the wet cake.
- Providing homogenous drying throughout the batch by gently mixing (ploughing) powder.
As an early pioneer of containment technology, PSL enhances its filtration and drying solutions with unique high-containment systems.
Many industrial filtration and drying processes require integrated containment technology in order to protect operators from highly toxic compounds and/or to protect sensitive products from the production environment. PSL containment systems can be integrated to allow end-users to complete a large range of process operations such as product sampling and product discharge while protecting the product integrity and maximising product yield.
PSL offer a range of containment solutions for integration with our filter dryers. Selection is based on the containment performance requirement and/or organisational preference for either rigid containment or flexible/disposable solutions.
ANFD are a mainstay in fine chemical and pharmaceutical manufacturing. Find out why with this brief overview of ANFD technology.
Features and Benefits
The GFD®Lab is an all-in-one filter dryer designed to comply with Good Laboratory Practices (GLP) for regulated research and development activities. It allows process developers and manufacturers to complete a wide range of processes in one single system:
- Slurry Filtration (solid-liquid separation)
- Product Washing
- Re-slurry
- Vacuum Drying
- Product Sampling
- Product Discharge
Unrivalled Product Recovery
At PSL, we understand your product is valuable. Therefore, maximising your product yield to remain competitive in your sector is vital.
The core features of the GFD®Lab are designed to address this crucial requirement. Upon process completion, your product batch can be easily collected by simply removing the unique filtration basket from the GFD®Lab vessel.
Additionally, the GFD®Lab basket is designed to allow quick and easy changeover of filtration meshes with various pore-sizes and materials (Polypropylene, PTFE, 316LSS, Alloy 22, etc.), hence facilitating multi-product applications.
Flexible Modular Design
The GFD®Lab is an innovative agitated nutsche filter dryer with a modular design that enables end-users to interchange vessels sizes from the 010 and 050 series without the need to use a different base frame.
To further enhance production flexibility, the base frame of each GFD®Lab model is also compatible with all available vessel materials (i.e. borosilicate glass, 316LSS, Alloy 22)
GFD Lab PLUS, Your Fast-Lane to Production
Due to its unique modular design, it is possible to upgrade the standard GFD®Lab Filter Dryer into a GFD®Lab PLUS model by simply retrofitting a new base frame to the existing vessel. By opting for this upgrade, the additional features allow you to speed-up development activities by automating the controls of your GFD®Lab.
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Digital display (42 colour HMI touchscreen)
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Enhanced user-interface allowing quick navigation
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Real-time process graph display
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Design process sequences
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Optimise and save process recipes (up to 99)
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Record and export process data
Batch Reproducibility, at the Touch of a Button
The GFD®Lab PLUS allows users to build bespoke process sequences and optimise process recipes to suit particular process applications.
Production can start at a touch of a button and pre-designed recipes can be initiated with your preferred process parameters (e.g. pressure/vacuum, agitator speed/torque, temperature, duration), thus maximising batch-after-batch reproduction while minimising human error.
Predictive Scale-up
Selecting the right process technology at R&D stage is crucial to ensure ultimate scale-up success. PSL’s GFD® Nutsche Filter Dryers are designed to streamline scale-up development from early R&D activities with the GFD®Lab, up to GLP batches and Pilot Plant Production using the GFD®Pilot.
It is perfectly suited to complete scale-up and scale-down studies as it helps maintain, at every scale, your key process objectives (e.g. product quality, product yield, batch consistency, etc.) and key production parameters (e.g. filtration time, washing time, drying time, etc.).
Be Containment-Ready with the GFD® Filterbox
Being one of the early pioneers of containment technology, PSL has developed the unique FilterBox isolator range which can successfully accommodate every GFD®Lab vessel size (010, 050 and 500 series).
By opting for a GFD®Lab FilterBox, operators are safe-guarded from the most toxic/potent compounds and that your product is protected from production environments.
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