4 services found
Creative Bioarray services
creative bioarray - FISH Probe Design
With access to the entire RP11 BAC library, Creative Bioarray is capable of developing custom FISH probes. Apart from that, we also offer mRNA ISH/FISH Probes, miRNA ISH/FISH Probes, and lncRNA ISH/FISH Probes. Custom probes can contain up to four fluorescent dyes and can be produced in lot sizes that meet your specific requirements.
creative bioarray - Transgene Mapping
For transgenic cell lines and transgenic animals generated via many methods, the integration site is random and in most cases not known. Integration of a transgene can disrupt an endogenous gene, potentially interfering with interpretation of the phenotype. In addition, knowledge of where the transgene is integrated is important for planning of crosses between animals carrying a conditional allele and a given Cre allele in case the alleles are on the same chromosome.
creative biogene - yeast one hybrid
Yeast one-hybrid system (Y1H), a variant of the yeast two-hybrid system (Y2H), is a powerful and commonly used in vivo genetic assay for identification of protein-DNA interactions. Y1H is a gene-centered (DNA-to-protein) approach, which has the advantages of being simple and efficient and can detect protein-DNA interactions in vivo.
creative bioarray - HSP90 Screening Services
Heat shock protein (HSP90) belongs to a family of molecular chaperones which are rapid and abundantly induced by stresses. HSP90 plays a crucial role in stabilizing denatured proteins that have become misfolded or unfolded because of cellular stress and by aiding in their re-folding. So far, many of the proteins identified as HSP90 clients are key components of the oncogenic phenotype involved in controlling many of the hallmarks of cancer.
