Celldeg has created a technology for photoautotrophic high-density cultures that enables an extremely efficient use of light with extremely high intensity for the production of biomass or bioproducts in the research and preparative scale.

A main reason for the handicap of low cell density in present-date photobioreactors can be seen in the limited use of light in some distance from the irradiated area and sub-optimal turbulent mixing of the culture by the gas-bubble flow.

Innovative culture vessels and photobioreactors for rapid growth of microalgae and cyanobacteria to ultra-high density. We are a team of experts in cyanobacterial biology, bioinformatics, and engineering offering innovative membrane-based bioreactor solutions for high density cultivation applications.

High density cultivators are now available with various culture volumes. The Celldeg technology is basing on bubble-free membrane-mediated CO₂ supply combined with the well-known increase of the quantum yield by strong turbulent mixing in high density cultures.

Celldeg´s patented Technology

Celldeg provides innovative and flexible systems for axenic culture of cyanobacteria and microalgae. The user-friendly High-Density Cultivators enable rapid growth up to extremely high biomass concentrations. Biomass yields are about 10 times higher than those reached with classic bubble-stream techniques. The cultivators can be easily fitted to very different approaches in microalgae research and bioprocess development.

Thin culture layer and membrane mediated CO₂ supply. Core elements of the cultivators are two chambers separated by a thin highly gas-permeable membrane of excellent biocompatibility and mechanical strength. The lower chamber contains air enriched with CO₂. The CO₂ concentration (usually 1-10%) can be maintained by a carbonate buffer (HDC with volume up to 150ml) or by controlled CO₂ injection (HDCs with volumes over 150ml). The upper chamber contains the liquid culture and a turbulent gas phase, which is in diffusional exchange with the atmosphere. An oxygen release compartment with defined gas permeability prevents high oxygen partial pressure

CellDEG - Model HD10 - Cultivator